آنزیم های درمانی: عملکرد و پیامدهای بالینی جلد اول

{"id":3805218,"title":"آنزیم های درمانی: عملکرد و پیامدهای بالینی جلد اول","price":"۳۳۰‌,‌۰۰۰","ebook_price":"۱۶۵‌,‌۰۰۰","rent_3_price":"۸۲‌,‌۵۰۰","rent_6_price":"۹۹‌,‌۰۰۰","rent_12_price":"-۱","print_price":"۳۳۰‌,‌۰۰۰","front_cover":{"thumbnail":"/storage/files/styles/thumbnail/books/a35de1e3d0f8e42e/front.jpg","large":"/storage/files/styles/large/books/a35de1e3d0f8e42e/front.jpg","medium_rounded":"/storage/files/styles/medium_rounded/books/a35de1e3d0f8e42e/front.jpg","medium":"/storage/files/styles/medium/books/a35de1e3d0f8e42e/front.jpg","medium_zoom_fit":"/storage/files/styles/medium_zoom_fit/anonymous.jpg","medium_trans":"/storage/files/styles/medium_trans/books/a35de1e3d0f8e42e/front.jpg"},"back_cover":{"thumbnail":"/storage/files/styles/medium/anonymous.jpg","large":"/storage/files/styles/medium/anonymous.jpg","medium_rounded":"/storage/files/styles/medium/anonymous.jpg","medium":"/storage/files/styles/medium/anonymous.jpg","medium_zoom_fit":"/storage/files/styles/medium/anonymous.jpg","medium_trans":"/storage/files/styles/medium/anonymous.jpg"},"file":null,"print_book":0,"isbn":"ج.1 : 9786229478684 دوره : 9786229478677","lang":null,"cover_type":null,"dimension":null,"year":"۱۴۰۳","nobat_chap":1,"description":["<p class=\"MsoNormal\" dir=\"RTL\" style=\"text-align: justify; direction: rtl; unicode-bidi: embed;\"><span lang=\"AR-SA\" style=\"font-size: 14.0pt; line-height: 107%; font-family: 'B Nazanin';\">امروزه عرصه داروهای زیستی به سرعت در حال گسترش است و موجودات زیستی و محصولات آن ها را برای کاربردهای درمانی مورد کاوش قرار داده و به کار می گیرد. آنزیم ها بیوکاتالیست های درخور توجهی هستند که سرعت واکنش های بیوشیمیایی را چند برابر می کنند. آن ها دارای چندین ویژگی خارق العاده، مانند پتانسیل کاتالیزوری بسیار زیاد و اختصاصیت بالای سوبسترا هستند. این ویژگی های خارق العاده باعث بروز کاربردهای بالینی متنوعی برای این آنزیم ها شده است. آن ها به طور فزاینده ای برای درمان طیف گسترده ای از بیماری ها، به تنهایی و در ترکیب با سایر درمان ها، به کار می روند. آنزیم های عملکردی را می توان از گیاهان، حیوانات یا میکروارگانیسم ها جدا کرد؛ همچنین پیشرفت های 20 سال اخیر در زمینه فناوری زیستی منجر به ارایه انواع آنزیم های نوترکیب و درمان های موثر جایگزینی آنزیم شده است</span><span dir=\"LTR\" style=\"font-size: 14.0pt; line-height: 107%; mso-bidi-font-family: 'B Nazanin';\">.</span>","\r","<p class=\"MsoNormal\" dir=\"RTL\" style=\"text-align: justify; direction: rtl; unicode-bidi: embed;\"><span lang=\"AR-SA\" style=\"font-size: 14.0pt; line-height: 107%; font-family: 'B Nazanin';\">درمان جایگزینی آنزیم به طورمعمول برای جایگزینی آنزیم ازدست رفته یا دارای نقص در یک فرد مبتلابه سندرم کمبود آنزیم ارثی استفاده می شود. آنزیم ازدست رفته با تزریق آنزیمی که از بافت یا خون انسان یا حیوان خالص شده یا با تکنیک های نوترکیب جدید تولید می شود، جایگزین می شود. به طورمعمول، آنزیم برای نیمه عمر طولانی تر، فعالیت قوی تر، مقاومت در برابر تخریب یا هدف قرار دادن یک اندام، بافت یا نوع خاصی از سلول اصلاح می شود</span><span dir=\"LTR\" style=\"font-size: 14.0pt; line-height: 107%; mso-bidi-font-family: 'B Nazanin';\">.</span><span style=\"font-size: 14.0pt; line-height: 107%; font-family: 'B Nazanin';\"> <span lang=\"AR-SA\">کتاب آنزیم های درمانی به پیشرفت های اخیر در مورد آنزیم های درمانی نوترکیب و فناوری بالینی و دارویی آن ها پرداخته و مروری بر فرایند تولید، شناسایی، استراتژی های مهندسی و دارورسانی؛ همچنین کاربردهای بالینی چند آنزیم انتخابی به ویژه آنزیم آلکالین فسفاتاز و درمان هیپوفسفاتازی از طریق درمان جایگزینی آنزیم دارد</span></span><span dir=\"LTR\" style=\"font-size: 14.0pt; line-height: 107%; mso-bidi-font-family: 'B Nazanin';\">.</span>","\r","<p class=\"MsoNormal\" dir=\"RTL\" style=\"text-align: justify; direction: rtl; unicode-bidi: embed;\"><span lang=\"AR-SA\" style=\"font-size: 14.0pt; line-height: 107%; font-family: 'B Nazanin';\">با توجه به پیشرفت های چشمگیر دهه های اخیر در عرصه آنزیم های درمانی و درمان جایگزینی آنزیم در جهت جبران کمبود منابع به زبان فارسی در این موضوع آنزیمهای درمانی: عملکرد و پیامدهای بالینی(جلد اول) و کمک به جامعه پزشکی، دانشجویان علوم زیستی و دارویی، ترجمه این کتاب انجام گرفت. امید است که ترجمه فارسی این کتاب کمکی در راستای درک بهتراین عرصه باشد</span><span dir=\"LTR\" style=\"font-size: 14.0pt; line-height: 107%; mso-bidi-font-family: 'B Nazanin';\">.</span>",""],"pages_count":429,"keywords":null,"token":"a35de1e3d0f8e42e","created_at":"2024-11-13 08:47:11","updated_at":"2024-11-18 11:00:50","publisher_id":241,"deleted_at":null,"published_at":"2024-11-18 11:00:50","available_for_web":1,"publisher_title":"سازمان پژوهشهای علمی و صنعتی ایران","edition":null,"currency":"IRR","subtitle":null,"country":"iran","exclusive_rights":null,"not_for_sale":null,"rent_1_week_price":"-۱","meta_desc":null,"meta_title":null,"stock":100,"cache":1,"authors":[{"id":1932211,"title":"نیکلاس لابرو","meta_title":"نیکلاس لابرو","meta_description":"نیکلاس لابرو - 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